产品目录

分子量：Approximately 7.8kDa,a single,non-glycosylated polypeptide chain containing 73 amino acids.
储存条件：冷冻（-20℃）

概述

Murine CXCL2,also named MIP-2,is belonging to the CXC chemokine family.It is encoded by the gene CXCL2.CXCL2 shares 90%amino acid sequence with CXCL1/GROα.It is member of the intercrine alpha(chemokine C-X-C)subfamily of chemokines.This chemokine is secreted from a murine macrophage cell line.The functional receptor for CXCL2 has been identified as CXCR2.CXCL2 is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells.Similar to other GRO proteins,CXCL2 is potent neutrophil attractants and activators.In addition,it is also active toward basophils.The amino acid sequence of murine CXCL2 is 60%identical to human CXCL2.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human neutrophils is in a concentration range of 1.0-10ng/ml.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl.
内毒素	Less than 1 EU/μg of rMuMIP-2/CXCL2 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKVCLDPEAPLVQ KIIQKILNKG KAN

相关搜索：重组小鼠MIP-2/CXCL2，MIP-2/CXCL2, Murine